General Information

General Information

DRAVP ID DRAVPe01876

Peptide Name HPV-31 L1 Ctb

Sequence TTTPAKRKKTKK

Sequence Length 12

UniProt ID No entry found

Source Synthetic construct

Activity Information

Target Organism HPV

Assay luminescence assay

Activity

[Ref.15170645]human papillomavirus(HPV):inhibition of HPV virus-like particle cell entry(12±10% inhibition at 10 μg/ml); inhibition of pseudovirions infection(15±8% inhibition at 10 μg/ml).

Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity

No cytotoxicity information or data found in the reference(s) presented in this entry

Binding Target Not found

Mechanism No mechanism information found in the reference(s).

Structure Information

PDB ID None

Predicted Structure Download No predicted structure available

Linear/Cyclic Linear

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Stereochemistry L

Physicochemical Information

Formula C60H114N20O17

Absent amino acids CDEFGHILMNQSVWY

Common amino acids K

Mass 1387.69

Pl 11.39

Basic residues 6

Acidic residues 0

Hydrophobic residues 1

Net charge 6

Boman Index -5114

Hydrophobicity -221.67

Aliphatic Index 8.33

Half Life

Mammalian:7.2 hour
Yeast:>20 hour
E.coli:>10 hour

Extinction Coefficient cystines 0

Absorbance 280nm 0

Polar residues 4

Literature Information

Literature 1

Title Positively charged synthetic peptides from structural proteins of papillomaviruses abrogate human papillomavirus infectivity.

Pubmed ID 15170645

Reference J Med Virol. 2004 Jul;73(3):474-80.

Author Bousarghin L, Touzé A, Yvonnet B, Coursaget P.

DOI 10.1002/jmv.20114