General Information
DRAVP ID DRAVPe01883
Peptide Name HLFcin 1-49
Sequence GRRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDSPIQCIQA
Sequence Length 49
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism HPV
Assay Western blotting
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No mechanism information found in the reference(s).
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Cyclic
N-terminal Modification Free
C-terminal Modification Free
Other Modification Disulfide bonds between Cys10 and Cys46, Cys20 and Cys37.
Stereochemistry L
Physicochemical Information
Formula C244H403N85O66S5
Absent amino acids HLY
Common amino acids R
Mass 5743.71
Pl 11.24
Basic residues 11
Acidic residues 2
Hydrophobic residues 13
Net charge 9
Boman Index -15425
Hydrophobicity -85.1
Aliphatic Index 53.67
Half Life
Extinction Coefficient cystines 11250
Absorbance 280nm 234.38
Polar residues 12
Literature Information
Literature 1
Title The anti-papillomavirus activity of human and bovine lactoferricin.
Pubmed ID 17481742
Reference Antiviral Res. 2007 Sep;75(3):258-65.
Author Mistry N, Drobni P, Näslund J, Sunkari VG, Jenssen H, Evander M.