To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01934
Peptide Name AVP-p
Sequence LNLFKKTINGLISDSLVIR
Sequence Length 19
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism PICV
Assay Plaque reduction assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism that untimely deployment of fusion machinery by the peptide could render virions less able to engage in on-pathway receptor binding or endosomal fusion.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification Noen
Stereochemistry L
Physicochemical Information
Formula C98H170N26O27
Absent amino acids ACEHMPQWY
Common amino acids L
Mass 2144.59
Pl 9.99
Basic residues 3
Acidic residues 1
Hydrophobic residues 9
Net charge 2
Boman Index -1499
Hydrophobicity 53.68
Aliphatic Index 158.95
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 6
Literature Information
Literature 1
Title Inhibition of arenavirus infection by a glycoprotein-derived peptide with a novel mechanism.
Pubmed ID 24850726
Reference J Virol. 2014 Aug;88(15):8556-64.
Author Spence JS, Melnik LI, Badani H, Wimley WC, Garry RF.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.