General Information
DRAVP ID DRAVPe01945
Peptide Name TP1
Sequence SWLVNRDWFHDLNLPWTGSSAGTWQ
Sequence Length 25
UniProt ID No entry found
Taxon ID 64293
Source Synthetic construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Genome polyprotein
GenBank Genome polyprotein
Amino Acid position Genome polyprotein
Domain Accession ID Not Available
Nucleotide sequence ID JF895923
Molecular Type Genomic RNA
Chromosomal Position Not Available
Activity Information
Target Organism TMUV
Assay Plaque assay, Western blotting
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism TP1 functions through a mechanism that involves release of the viral genome and interference with cellular TMUV binding
Structure Information
PDB ID 6ZQJ
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C138H189N37O38
Absent amino acids CEIKMY
Common amino acids W
Mass 2974.24
Pl 5.19
Basic residues 2
Acidic residues 2
Hydrophobic residues 10
Net charge 0
Boman Index -3639
Hydrophobicity -59.2
Aliphatic Index 62.4
Half Life
Extinction Coefficient cystines 22000
Absorbance 280nm 916.67
Polar residues 9
Literature Information
Literature 1
Title Peptide inhibitors of tembusu virus infection derived from the envelope protein.
Pubmed ID 32456819
Reference Vet Microbiol. 2020 Jun;245:108708.
Author Zhao D, Zhang L, Han K, Liu Q, Yang J, Huang X, Liu Y, Li Y, Zhao P.