To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01951
Peptide Name Pep-CORE
Sequence DHVTPDIAYNP
Sequence Length 11
UniProt ID No entry found
Source Acacia catechu
Activity Information
Target Organism DENV
Assay Focus-Forming Unit (FFU) Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism the biding of peptide to virus particles might disrupt the ability of the virus to bind to the host cell receptor or possibly block the internalization of the virus into the host cells.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C55H80N14O19
Absent amino acids CEFGKLMQRSW
Common amino acids DP
Mass 1241.32
Pl 4.2
Basic residues 1
Acidic residues 2
Hydrophobic residues 3
Net charge -1
Boman Index -2068
Hydrophobicity -76.36
Aliphatic Index 70.91
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 149
Polar residues 3
Literature Information
Literature 1
Title Synthetic Bioactive Peptide Derived from the Asian Medicinal Plant Acacia catechu Binds to Dengue Virus and Inhibits Cell Entry.
Pubmed ID 33172110
Reference Viruses. 2020 Nov 6;12(11):1267.
Author Panya A, Sawasdee N, Songprakhon P, Tragoolpua Y, Rotarayanont S, Choowongkomon K, Yenchitsomanus PT.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.