To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01975
Peptide Name CHR-3, Env GP (633-668)
Sequence REINNYTSLIHSLIEESQNQQEKNEQELLELDKWAS
Sequence Length 36
UniProt ID P04578
Source Synthetic construct
Activity Information
Target Organism HIV
Assay ELISA
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism CHR-3 interacts with N46 to form unstable 6-HB
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C186H294N52O67
Absent amino acids CFGMPV
Common amino acids E
Mass 4330.69
Pl 4.42
Basic residues 4
Acidic residues 8
Hydrophobic residues 10
Net charge -4
Boman Index -10860
Hydrophobicity -120.28
Aliphatic Index 89.44
Half Life
Extinction Coefficient cystines 6990
Absorbance 280nm 199.71
Polar residues 10
Literature Information
Literature 1
Title HIV gp41 C-terminal heptad repeat contains multifunctional domains. Relation to mechanisms of action of anti-HIV peptides
Pubmed ID 17276993
Reference J Biol Chem. 2007 Mar 30;282(13):9612-9620.
Author Liu S, Jing W, Cheung B, Lu H, Sun J, Yan X, Niu J, Farmar J, Wu S, Jiang S.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.