To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02008
Peptide Name Peptide 10
Sequence SPRTGLDFNEMI
Sequence Length 12
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism DENV
Assay Antiviral assays(Cell protection assay, Direct virus inhibition assay, Post-infection assay, Viral attachment assay, Viral entry assay)
Activity [Ref.36739680]Peptide 10 (200 μM) exhibited inhibitions of all four DENV serotypes, with high inhibitions of DENV-4 at 81.13%, followed by DENV-3 at 60.47% and DENV-1 at 47.01%.
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C59H94N16O20S
Absent amino acids ACHKQVWY
Common amino acids DEFGILMNPRST
Mass 1379.55
Pl 4.37
Basic residues 1
Acidic residues 2
Hydrophobic residues 3
Net charge -1
Boman Index -2695
Hydrophobicity -45.83
Aliphatic Index 65
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Literature Information
Literature 1
Title Development of novel antiviral peptides against dengue serotypes 1-4.
Pubmed ID 36739680
Reference Virology. 2023 Mar;580:10-27.
Author Lee MF, Anasir MI, Poh CL.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.