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General Information
DRAVP ID DRAVPe02029
Peptide Name P10
Sequence RNTREVFAQVKQMYKTPTLKYFG
Sequence Length 23
UniProt ID P59594
Taxon ID 694009
Source synthetic Construct (Derived from SARS-CoV: 694009)
Validation Experimentally Validated
Origin Information
Gene Name/ID S2 (918758),
GenBank AY278741.1
Amino Acid position amino acid residues fragments (758–780)
Domain Accession ID cd22378
Nucleotide sequence ID AY278741
Molecular Type Genomic RNA
Chromosomal Position N/A
Activity Information
Target Organism SARS-CoV
Assay Syncytia inhibition assay
Activity Not Avaialble
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Spike Protein
Mechanism P10 antisera had specific binding to the S fragments and S protein expressed in E. coli and SARS‐CoV infected cell lysates, suggesting that those Abs have a potential to recognize S protein of SARS‐CoV in its natural form
Structure Information
PDB ID 5XJK
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C128H201N35O34S1
Absent amino acids CDHISW
Common amino acids KTEQRY
Mass 2806.6
Pl 10.58
Basic residues 5
Acidic residues 1
Hydrophobic residues
Net charge 4
Boman Index
Hydrophobicity -0.865
Aliphatic Index 46.52
Half Life
Extinction Coefficient cystines 2980
Absorbance 280nm 1.06
Polar residues
Literature Information
Literature 1
Title Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential
Pubmed ID 15811330
Reference Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential. FEBS letters, 579(10), 2130–2136. https://doi.org/10.1016/j.febslet.2005.02.070
Author Xia, S., Liu, M., Wang, C., Xu, W., Lan, Q., Feng, S., Qi, F., Bao, L., Du, L., Liu, S., Qin, C., Sun, F., Shi, Z., Zhu, Y., Jiang, S., & Lu, L. (2020)
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.