General Information


DRAVP ID  DRAVPe02151

Peptide Name   N/A

Sequence  SGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL

Sequence Length  34

UniProt ID  P0DTC2 

Taxon ID  2697049 

Source  HR segment of SARS-CoV

Validation   Experimentally Validated



Origin Information


Gene Name/ID  S2(43740568)

GenBank  QHD43416.1

Amino Acid position  1170-1203

Domain Accession ID  Not Available

Nucleotide sequence ID  MN908947.3 

Molecular Type  Genomic RNA

Chromosomal Position  Chromosome:21,563 - 25,384



Activity Information


Target Organism  SARS-CoV-2

Assay  antiviral Assay

Activity  Not Avaialble

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Glycoprotein. Gp41

Mechanism  ting the virus’ action before adsorption, at a percentage above



Structure Information


PDB ID  6LVN  6LXT  6LZG 

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Cyclic

N-terminal Modification  N-terminal leucine/isoleucine zipper-like sequence

C-terminal Modification  C-terminal heptad repeat located upstream

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  C162H276N46O57

Absent amino acids  RDCHMPWOU

Common amino acids  NL

Mass  3780.25

Pl  4.36

Basic residues  3

Acidic residues  6

Hydrophobic residues  18

Net charge  -3

Boman Index  0.9

Hydrophobicity  -0.218

Aliphatic Index  134.71

Half Life 

  •     Mammalian:1.9 hours
  •     Yeast:>20 hour
  •     E.coli:>10 hours

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  22



Literature Information


Literature 1

Title   Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy

Pubmed ID   14499001

Reference   BMC microbiology, 3, 20.

Author   Kliger, Y., & Levanon, E. Y. (2003).

DOI   10.1186/1471-2180-3-20