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DRAVP ID DRAVPa2212
Peptide Name Sequence 11 from Patent CN116874560A
Sequence KYWGRN
Sequence Length 6
Source Synthetic peptide
Target Organism FAdV-4
Patent Type Patent Application
Publication Date 2023-10-13
Patent No CN116874560A
Patent Title Antiviral affinity peptide targeting fowl adenovirus 4 type Fiber2 protein and application thereof
Comment
Abstract The invention provides an antiviral affinity peptide targeting fowl adenovirus 4 type Fiber1 protein and application of the antiviral affinity peptide. The sequence of the affinity peptide is YMKHRV. According to a three-dimensional structure of a spike protein Knob structural domain, the affinity peptide targeting the Fiber1Knob structural domain is designed by utilizing a computer virtual screening technology. According to the present invention, the active pocket docking range is selected, the in vitro test screening is performed to obtain the optimal peptide having the antiviral activity on FAdV-4, the clue and the theoretical support are provided for the further research on the virus receptor and the antiviral drug design, and the new thought is provided for the prevention and the control of the FAdV-5 infection in the future.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.