To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVPR ID DRAVPR0009
Name Neuromedin-B
Sequence
Sequence Length 121
Source Mus musculus (Mouse)
UniProt ID Q9CR53
Gene Nmb
Activity Information
Target Organism IAV
Activity
Structure Information
PDB ID None
Predicted Structure Download AF-Q9CR53-F1
Modification The Met at position 56 is amidation.
Comment
It is likely that NMB plays an anti-inflammatory role via the regulation of the host type I IFN signalling pathway. The NMB/NMBR system appeared to increase IFN-α expression and decrease IL-6 expression after PR8 infection, which may serve to establish an antiviral state in the host.
Literature Information
Literature 1
Title Role of neuromedin B and its receptor in the innate immune responses against influenza A virus infection in vitro and in vivo.
Pubmed ID 31601264
Author Yang G, Huang H, Tang M, Cai Z, Huang C, Qi B, Chen JL.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.