General Information
DRAVPR ID DRAVPR0012
Name Interferon-stimulated gene 20 kDa protein(ISG20)
Sequence
Sequence Length 181
Source Homo sapiens (Human)
UniProt ID Q96AZ6
Gene ISG20
Activity Information
Target Organism HCV,HAV,YFV
Activity
Structure Information
PDB ID 1WLJ
Predicted Structure Download AF-Q96AZ6-F1
Modification No modifications on the sequence.
Comment
ISG20 is an interferon-inducible 3′–5′ exonuclease that inhibits replication of several human and animal RNA viruses.
Literature Information
Literature 1
Title Antiviral activities of ISG20 in positive-strand RNA virus infections.
Pubmed ID 21036379
Author Zhou Z, Wang N, Woodson SE, Dong Q, Wang J, Liang Y, Rijnbrand R, Wei L, Nichols JE, Guo JT, Holbrook MR, Lemon SM, Li K.
Literature 2
Title ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses.
Pubmed ID 12594219
Author Espert L, Degols G, Gongora C, Blondel D, Williams BR, Silverman RH, Mechti N.