To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVPR ID DRAVPR0021
Name Interferon alpha-11(Limitin)
Sequence
Sequence Length 190
Source Mus musculus (Mouse)
UniProt ID Q61716
Gene Ifna11
Activity Information
Target Organism No specific virus mentioned in the entry
Activity [Ref.22912583]IFN-α11-mediated activation of NK cells enabled cytolytic killing of FV-infected target cells via the exocytosis pathway.
Structure Information
PDB ID None
Predicted Structure Download AF-Q61716-F1
Modification ①Glycosylation of Asn at position 101.②There are two disulfide bonds between Cys24 and Cys122, Cys52 and Cys162.
Comment
IFN-α11 significantly reduced viral loads during Friend retrovirus infection (FV).
Literature Information
Literature 1
Title Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection.
Pubmed ID 22912583
Author Gibbert K, Joedicke JJ, Meryk A, Trilling M, Francois S, Duppach J, Kraft A, Lang KS, Dittmer U.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.