General Information
DRAVPR ID DRAVPR0027
Name DNA dC->dU-editing enzyme APOBEC-3A
Sequence
Sequence Length 199
Source Homo sapiens (Human)
UniProt ID P31941
Gene APOBEC3A
Activity Information
Target Organism HTLV-1,AAV
Activity
Structure Information
PDB ID 2M65 4XXO 5KEG 5SWW 7D3V 7D3W 7D3X
Predicted Structure Download AF-P31941-F1
Modification No modifications on the sequence.
Comment
Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons.
Literature Information
Literature 1
Title APOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T-lymphotropic virus type 1.
Pubmed ID 22457529
Author Ooms M, Krikoni A, Kress AK, Simon V, Münk C.
Literature 2
Title APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons.
Pubmed ID 16527742
Author Chen H, Lilley CE, Yu Q, Lee DV, Chou J, Narvaiza I, Landau NR, Weitzman MD.