General Information


DRAVPR ID  DRAVPR0046

Name   Interferon epsilon

Sequence 

Sequence Length  192

Source  Mus musculus (Mouse)

UniProt ID Q80ZF2

Gene Ifne



Activity Information


Target Organism  HSV-2

Activity 

  • [Ref.23449591]Herpes simplex virus 2(HSV-2):Interferon-ε directly protects from viral infection.



Structure Information


PDB ID  None

Predicted Structure Download  AF-Q80ZF2-F1

';

Modification  There is a disulfide bond between Cys52 and Cys162.



Comment


IL-17A was implicated in priming T cell responses during lymphocytic choriomeningitis virus (LCMV) hepatitis and mediating the immunopathogenicity of viral infections, such as influenza virus, respiratory syncytial virus, murine encephalomyelitis virus, and hepatitis B virus infections.



Literature Information


Literature 1

Title   Interferon-ε protects the female reproductive tract from viral and bacterial infection.

Pubmed ID   23449591

Author   Fung KY, Mangan NE, Cumming H, Horvat JC, Mayall JR, Stifter SA, De Weerd N, Roisman LC, Rossjohn J, Robertson SA, Schjenken JE, Parker B, Gargett CE, Nguyen HP, Carr DJ, Hansbro PM, Hertzog PJ.