General Information


DRAVPR ID  DRAVPR0127

Name   NFX1-type zinc finger-containing protein 1

Sequence 

Sequence Length  1918

Source  Homo sapiens (Human)

UniProt ID Q9P2E3

Gene ZNFX1 (KIAA1404)



Activity Information


Target Organism  No specific virus mentioned in the entry

Activity  [Ref.33872655]RNA-binding protein that initiates the antiviral response and is required to restrict the replication of RNA viruses



Structure Information


PDB ID  None

Predicted Structure Download  AF-Q9P2E3-F1

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Modification  No modifications on the sequence.



Comment


No comments found in the entry



Literature Information


Literature 1

Title   Multisystem inflammation and susceptibility to viral infections in human ZNFX1 deficiency

Pubmed ID   33872655

Author   Vavassori S, Chou J, Faletti LE, Haunerdinger V, Opitz L, Joset P, Fraser CJ, Prader S, Gao X, Schuch LA, Wagner M, Hoefele J, Maccari ME, Zhu Y, Elakis G, Gabbett MT, Forstner M, Omran H, Kaiser T, Kessler C, Olbrich H, Frosk P, Almutairi A, Platt CD, Elkins M, Weeks S, Rubin T, Planas R, Marchetti T, Koovely D, Klämbt V, Soliman NA, von Hardenberg S, Klemann C, Baumann U, Lenz D, Klein-Franke A, Schwemmle M, Huber M, Sturm E, Hartleif S, Häffner K, Gimpel C, Brotschi B, Laube G, Güngör T, Buckley MF, Kottke R, Staufner C, Hildebrandt F, Reu-Hofer S, Moll S, Weber A, Kaur H, Ehl S, Hiller S, Geha R, Roscioli T, Griese M, Pachlopnik Schmid J.